![]() ![]() We did not identify any risk factor for ASD but found a negative correlation between the ADI-R score and adaptive functioning level. The frequency of autistic traits in the entire group was a continuum. Among 46 participants with complete results for the Autism Diagnostic Interview-Revised (ADI-R), 13 (28%) had a diagnosis of autism according to the ADI-R, and 25 (54%) had a diagnosis of autism spectrum disorder (ASD) according to the DSM-5 criteria. We investigated 64 individuals with CHARGE syndrome (35 females mean age 10.7 years, SD 7.1 years). ![]() We evaluated their adaptive functioning level and sensory particularities and extracted several data items from medical files to assess as potential risk factors for autism and/or behavioral disorders. In a large national cross-sectional study, we used specific standardized tools for diagnosing autism (Autism Diagnostic Interview-Revised and Diagnostic and Statistical Manual of Mental Disorders, 5th edition, DSM-5) and evaluating behavioral disorders (Developmental Behavior Checklist-Parents, DBC-P) to investigate a series of individuals with CHARGE syndrome, defined by Verloes’s criteria. The similarity of their behavioral traits with those of people with autism raises questions. ![]() Behavioral problems are an important issue for people with CHARGE syndrome. ![]()
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